Study Population

Inclusion Criteria

• ≥55 years of age
• At high risk for cardiovascular disease:
  • Coronary artery disease
  • Peripheral arterial occlusive disease
  • Stroke or recent transient ischaemic attack
  • Diabetes with end-organ damage
• Intolerant to ACE inhibitors

Exclusion Criteria

• Overt heart failure
• Arterial hypertension (>160/100 mmHg)
• Diabetic patients with proteinuria

References